Endocrine Abstracts

Diabetes mellitus disturbs cellular metabolism of all organs and systems, including myocardium. The disturbances in cardiomyocytes lead to changes of QT and QTc intervals prolongation. Research: to evaluate values of intervals QT and QTc in children with diabetes mellitus type 1 (DM1) and to reveal interrelation of the given changes with the duration of disease, age, sex, indices of metabolic control.Materials and methods: QT and QTc were evaluated on EC...

The basic manifestations of dystrophic changes in heart of children suffering form diabetes mellitus type 1 (DM1) are disturbances of repolarization and depolarization processes, including QT and QTc intervals prolongation. Research objective: to evaluate indices of QT and QTc in children with DM1, to reveal interrelation of the observed changes with the duration of disease, age, sex, levels of cholesterol (CH) and glycemie, BMI, blood pressure, pulse rate.<p class="abstex...

The basic manifestations of dystrophic changes in heart of children suffering from diabetes mellitus type 1 (DM1) are disturbances of repolarization and depolarization processes, including QT and QTc intervals prolongation. Research objective: to evaluate indices of QT and QTc in children with DM1, to reveal interrelation of the given changes with the duration of disease, age, sex, levels of cholesterol (CH), of glycemie, BMI, blood pressure, pulse rate....

Background and aims: High correlation is revealed between type 1 diabetes mellitus (DM1) and autoimmune thyroid pathology in children. Several candidate-genes including CTLA, PTPN, Ins-23Hphl could be associated with the combined autoimmune endocrinopathy. The aim of this study was to define whether polymorphisms of CTLA 49 A/G, PTPN22-1858 C/T, Ins-23Hphl ?/? genes contribute to DM1 and autoimmune thyroiditis (AT) combination development.Material and me...